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March 31 2000 Nick Miron is painting the bunkroom

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first_imgMarch 31, 2000Nick Miron is painting the bunkrooms during camp synergy. Photo by: DoctressNeutopialast_img

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Nick Percy BBC Worldwide BBCWW has named Nick Pe

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first_imgNick PercyBBC Worldwide (BBCWW) has named Nick Percy as executive vice president in Western Europe.Percy replaces Tobi de Graaff, who has been given a newly created role as director of commissioning and coproduction.Percy will take over de Graaff’s former role on September 1 at BBCWW’s London office. The role will have him oversee all of the company’s business activities in Western Europe, which consists of Benelux, France, Germany, Iberia, Italy and the Nordics.Percy’s remit includes responsibility for BBCWW’s sales clients, the Northern European channels portfolio and production bases in France, Germany and the Nordics.De Graaff’s role will be responsible for developing and executing commercial strategies for premium content. He will report to chief content officer Helen Jackson.Paul Dempsey, president of global markets at BBC Worldwide, said: “Nick is a successful leader whose understanding of the increasingly complex European landscape makes him perfectly suited to growing our business across these important markets.”last_img read more

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Just about every time some troublemaker like myse

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first_imgJust about every time some trouble-maker like myself wants to question the practice of taxation, someone will ask: But aren’t taxes the price of civilization? This is how people hope to get rid of us with a single shot. Usually, they do it in some sort of cocktail-party setting, where they can throw out their line, then move away before a proper response is made. (And while the other “right-thinking” folks nearby scowl properly.)  Conversation over – they win. Except, of course, that the slogan is ridiculous: People pay taxes in non-civilized places too! Any time anyone can make himself boss, he takes a cut of everything he can. And there’s a name for that – taxes! Let me throw out another question: Is the United States ten times more civilized than it was a hundred years ago? Have the crime rates really fallen by 90 percent? Well, we’re paying about ten times as much in taxes – shouldn’t they? Here’s an even better example: Communist China had an effective tax rate that approached 100% under Mao. Were they the most civilized society that ever existed? Indeed, I could pull out the old history book and find plenty of other great examples where the level of taxation and the level of civilization had absolutely no correlation to each other. Let’s get this straight: Rulers tax as much and as often as they can. And this statement is confirmed by every single page of the history of the world. The mark of a civilized society is that it can restrain rulers and their take of production. Taxes are not the price of civilization. They are the price we pay for our unwillingness to control government. Paul Rosenberg FreemansPerspective.com [“Are Taxes the Price of Civilization?” s an excerpt from Paul Rosenberg’s book, Mindless Slogans – 101 Cheap Substitutes for Actual Thought]last_img read more

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The EU continues its chainsaw juggling act The au

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first_imgThe EU continues its chainsaw juggling act. The austerity pledge from France is holding about as well as its Maginot Line, while Greece has sworn to meet its fiscal targets in 2014 2015 2016 soon, and the Italians promise they’re going to kick some serious fiscal butt as soon as the country returns from holiday. Spain reassures that it will squarely confront its need to raise worker productivity whenever the unions call an end to protests against austerity. And the Portuguese high court ruled it is unconstitutional for civil servants to work for less than twice the wages of their private-sector counterparts. This chronic “the sky is falling” in the EU had induced investor news-cycle fatigue and rendered last year’s black-swan threat level from red to this year’s collective yawn… … until Cyprus tossed another chainsaw into the act. The Cyprus looting of private wealth was a cold-shower reminder of the tenuous security of assets that are concentrated within reach of a single government – doubly true of nations in a desperate fiscal situation whose financial sector is about to topple. DepositorCreditor The blatant theft of depositor money in Cypriot banks was at first peddled as a one-off emergency measure. Then a Freudian slip by the head of the Eurogroup finance ministers, Mr. Dijsselbloem, suggested this would be the new pattern for similar future events. Much back-pedaling and “clarification” ensued. But don’t bother squinting as you try to read the lips of mumbling bureaucrats. Just follow what they’re doing and you won’t get blindsided. What have they been up to? In October 2011, the Financial Stability Board (FSB) – a tentacle of the Bank for International Settlements, the central bank for central bankers – released a report that proposed a new regime to resolve financial-institution instability. In the report, the FSB calls for solvency support for banks without taxpayer exposure and the allocation of losses to shareholders and unsecured and uninsured creditors. Deposits at a bank are considered a loan, and if a bank fails, its depositors become unsecured creditors for amounts that exceed the insurable limit. It gets worse. To protect the integrity of the financial system, controls on both endogenous (the bank itself) and exogenous (other firms and cross-border cooperation) capital movement can be implemented. This is exactly what happened in Cyprus. To prevent capital flight out of the banking system, the movement of money out of or between banks was restricted, as well as capital sent outside the country. The G20 has fully endorsed the plan, and its implementation is complete or under way in member jurisdictions. The US is a G20 member, so don’t kid yourself into believing it can’t happen in America. It can and will. The Cyprus event has been carefully framed as an anomaly when in fact it is part of a well-orchestrated script. In the Year of Our Overlord 1 AF January 1, 2014, will mark the start of Year 1 AF – “after FATCA.” In the run-up to the US reporting regime’s full implementation, many foreign banks have opted not to accept US persons as clients, and we can see why. FATCA is a huge burden on foreign financial institutions in terms of time and resources needed to identify, track, and report on their US clients. Today, it is nearly impossible to find a foreign bank that will open an account for an American without them visiting the bank and delivering a stack of notarized paperwork to prove they are who they say they are. Other banks that had welcomed US persons have suspended doing so in anticipation that further demands on their time will be announced. In fact, one bank we spoke with during our research on internationalization has done just that. Lloyds TSB has stopped opening accounts for Americans, pending a review of FATCA later this year. Our contact at the bank did not sound optimistic that the policy would be reversed. This is a trend we expect will gain traction. And as if Americans seeking to internationalize weren’t already facing stiff headwinds, a recent leak of internal documents linked to offshore entities will likely add some force. In early April, millions of emails and other records were leaked with information on thousands of account and company owners in the British Virgin Islands, a popular offshore banking center. The leak exposed several high-profile clients that are allegedly “hiding” assets from their home tax authorities. This is just the kind of news that will embolden the offshore-means-tax-evasion governmenteers to twist the reporting screws a little bit tighter. When Is Now The incremental creep of crises continues to aggravate the financial landscape and provokes increasingly desperate responses from Western governments, particularly the US. Yet in spite of all the words unleashed and regulations imposed against offshore investing, it remains unquestionably legal. How long it will continue to be legal is questionable. Is it easy? No. But neither is getting your luggage and shoes through airport security. The situation for the easy movement of capital and assets across borders is dire, but it is not hopeless if you have the right information. FATCA has effectively acted as stealth capital controls, as the regulations dissuade foreign financial institutions from doing business with Americans, discouraging all but the most persistent investors from pursuing an international wealth preservation strategy. As the pieces come together, a clear picture emerges: Americans are just one financial crisis away from triggering the provisions of the G20-backed FSB financial resolution regime. And that almost certainly will include restrictions on the movement of capital. Once your money is trapped inside the US, any type of concocted emergency “tax” can be imposed on your wealth. Additional taxes are just one of many steps your home government can take to grab a share of your hard-earned wealth. Wise investors disperse their assets internationally to minimize this risk, and though it’s getting late in the game, there’s still time for you to join them. You can learn about moving your cash offshore… setting up an offshore LLC… investing in international stock markets… and internationalizing yourself, including getting a second passport. It’s all available in an information-packed special report titled Going Global 2013. You won’t find a better resource for internationalizing your life and your assets. Get started today.last_img read more

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Gold Producers GDX 2801 2403 49

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first_img Gold Producers (GDX) 28.01 24.03 49.13 Louis James Senior Metals Investment Strategist Casey Research Gold 1,388.80 1,282.60 1,703.20 TSX (Toronto Stock Exchange) 12,820.92 12,469.32 12,139.73 TSX Venture 954.92 912.83 1,258.30 One Year Ago Rock & Stock Stats Last Silver Stocks (SIL) 15.29 12.12 22.23center_img One Month Ago Oil 110.53 105.30 95.53 Dear Reader, We’ve written recently—and many times before—about the foolishness of trying to time a market. In hindsight, however, market peaks and troughs become increasingly obvious. In a recent conversation with Doug Casey, he told me that the general uptrend in gold since June is evidence that the general downtrend since September 2011 has ended. While Doug is not omniscient, I’ve seen him when his speculator’s instinct kicks in—and over the years its accuracy has been nothing short of astounding. It seems that instinct is now telling him that gold and gold stocks have bottomed. Of course, if the Fed announces a tapering of its money printing this month, that would likely whack gold again. Depending on how drastic the language of the Fed announcement is, we could see a renewed sense of panic among gold investors, and the actual bottom for this correction could be just ahead of us rather than just behind us. Either way, prices are already low. Ben Bernanke said he would only turn down the government’s printing presses if employment figures improved substantially. Since those remain rather weak, there may not be any tapering announcement at all this month, and if there is, it will likely be marginal—a toe in the water. It’s also worth pointing out that if Doug is right about the US economy finally exiting the eye of the storm, there will likely come a “moment of truth” when people realize that the inevitable has become imminent and every asset class across the board gets hit, including gold. That downturn will be enduring for many assets—permanent for some, but very short-lived for gold. It may turn out to be the last great buying opportunity in this gold bull market, but it could well happen at prices much higher than today’s, so we don’t intend to keep our money on the sidelines waiting for it. In other words: yes; we are buyers today. Our article below describes the sort of opportunities we are seizing today. It is, I freely admit, something of a sales pitch for the Casey International Speculator—but if Doug is right about the gold market having bottomed, there’s never been a better time to subscribe and find out what he himself is buying. Sincerely, Copper 3.23 3.17 3.52 Gold Junior Stocks (GDXJ) 47.42 37.12 91.12 Silver 23.84 19.52 32.62last_img read more

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In This Issue   Jobless claims at 8 year low

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first_imgIn This Issue. *  Jobless claims at 8 year low *  New home sales plummet *  Dollar up across the board *  Kiwi got crushed And Now. Today’s A Pfennig For Your Thoughts. In a holding pattern until next week. Good Day. And welcome to Friday morning. The weekend is nearly upon us and it couldn’t have gotten here fast enough. We were having issues with the server yesterday so I apologize if the Pfennig arrived late or if you received a duplicate copy. Aaron yelled over to me yesterday morning and said the title of the Pfennig was very appropriate since he got it twice. Anyway, the headlines were rather plentiful, so let’s jump right in. We had an active day not only in the currency market but we also had a decent load of data to pick through as well. The print which really got things moving was the weekly jobless claims. The expected result among many economists was for a slight rise to 307k from the previously reported figure of 302k, so it was largely being brushed off as a snoozer. Well, things didn’t go exactly as planned. Instead, the number of Americans filing new claims for unemployment benefits fell to 284k, which was the lowest level since Feb 2006. The less volatile four week average fell to 302k, which was the lowest since May 2007, from the previous reading of 309,250. There was also improvement in continuing claims as we them fall to a seven year low of 2.5 million. News of these improvements really woke up those in the interest rates are going higher soon that we think camp. Anyway, the Labor Department said there was nothing unusual or special factors influencing the data, but indicated jobless claims then to be volatile around this time of the year due to automakers retooling plants which often requires a shut down. With that being said, a few analysts are pointing to the red hot auto industry as the reason we saw such improvement and ultimately lends itself to the question as to whether this will be a temporary thing. Just to give you an idea, the states of Michigan and Ohio were among those who experienced the largest decrease in claims. Given that coincidence, some think this report actually gives more credence to manufacturing than the labor market. July is typically an off month for auto manufacturing since many plants shut down for at least a couple weeks to re-tool for the new models. It doesn’t look like that is happening this summer since demand has been crazy, which may have contributed to this anomaly. I don’t want to discount the fact that this is a big positive for the labor market, but I think a more pragmatic approach is still needed before we start saying employment is officially in the clear and out of the woods. On the flip side, we had June new home sales show quite a bit of disappointment. First, let me set this up for you. The initial expectations were calling for sales to come in at annual pace of 475k. Instead, new home sales fell 8.1% in June to 406k and marked the biggest decline since June 2013. More disturbing, though, was the downward revision to May’s number. If you recall, the original numbers from May were very good and had many crowing about the housing market. At the end of the day, the May reading saw the largest ever downward revision as sales were reduced from 504k down to 442k, which was over a 12% revision. The next logical question is why the large correction. Sales of new homes are counted when the purchase contract is signed, so what’s happening between contract signing and actual closing. I wasn’t able to come across any explanations, but I’m sure financing, or a breakdown thereof, would be a central candidate. New homes only account for about 7.5% of the housing market so it’s a fairly small piece of the pie but disturbing news in what has otherwise been a bright spot. In other news, the KC Fed manufacturing report came in better and falls in line with many of the other regional reports showing expansion. In other manufacturing numbers, we also had the Markit Economics preliminary index of US manufacturing moderate a bit in July from the four year high in June, but still showing a decent trend of expansion. Speaking of the Markit reports and a nice segue into currencies, Chuck had this to share with us: “Don’t know if you saw this, but HSBC/ Markit published their version of Chinese manufacturing Index (PMI) on Thursday afternoon, and showed that the index has risen to 52. A 51 was the estimate, and the previous month’s index number was 50.7.. So, all in all , it’s just another brick in the Wall.   Remember it was me that told you not to listen to all those that said China’s economy would have already collapsed by now, and that I believed the economy had troughed in the 2nd QTR.  So, given that, I take this time to slap myself on the back, and move on to other things. The Chinese renminbi/ yuan did react favorably to the news, and that was a good thing. Fundamentals have left the market, as everything is Central Bank driven these days, but for once, a fundamental moved a currency! YAHOO!  Now. back to our regularly scheduled programming, and here’s Mike!” Thanks Chuck. Seeing that Chinese manufacturing index at an 18 month high was good news for the global economy. The dollar buying bias has remained with us all day long, albeit muted against all currencies except for the New Zealand dollar. The euro was down in early trading after we saw all of the US data, but recovered nicely and ended the day right where it began. We definitely saw more volatility in the markets yesterday as the euro had a range of 50 basis points between the high and low, but trading was still on the flatter side. Chuck sent more thoughts my way, so here’s what he had to say: “I received some info from a chart guru, and well known analyst, who used to be with RBC, TJ Marta, yesterday. and his charts tell him that the euro is showing signs of bottoming, with momentum oversold, and RSI (relative strength index) up from low since May. He thinks the short term move could be 1 to 1.8%…  the same kind of stuff holds true for the New Zealand dollar / kiwi, so there you have the view from the charts guru.  Long time readers know that I’m not sold on charts, but do believe that they can help explain moves.  So, here’s to the charts on these two currencies!” Its Mike again. Speaking of the New Zealand dollar, it just couldn’t pick itself up off the mat after getting caught with a right hook square in the jaw. As I mentioned yesterday, the central bank went very dovish on us so the kiwi finished up in last place with a 1.5% loss. Just to give you an idea, the second to worst currency was the Aussie with a loss of 35 basis points. The straw that stirred the drink were the several references made as to how high the kiwi is right now. Comments such as unjustified strength of the currency and unsustainable used as descriptions for the currency pretty much did it in. Concern about the strength of the kiwi is nothing new as it seems like policy makers take every opportunity they can to jawbone the currency lower, but this time, they got the desired kneejerk reaction. With that said, the kiwi has strengthened its case as a destination for carry trade funds so we could see a pattern of buying on dips emerge. As I hit on earlier, the Aussie came in second place from the bottom but that was mainly due to sympathy pains to the kiwi. Not only that, a 30 something basis point loss isn’t exactly horrible. Inflation came in higher than expected so that has traders backing away from any rate calls in Australia. At the end of the day, we were back to the view interest rates in the US will be heading upward sooner than the general consensus. I think its safe to say that interest rates will go higher in the US before the Eurozone or Japan, but we’re still a long way off before that’s even a twinkly in the eye for Janet Yellen. Anyway, we also had July manufacturing surprise on the upside in the Eurozone but retail sales in the UK were lower than initial estimates. I think a lot of the hesitation in the markets this week has to do with what’s on tap next week for US data. We have some heavy hitting info such as second quarter GDP, a Fed meeting, and the July jobs number. I don’t think too many want to be heavily weighted on one side or the other heading into next week. As I came in this morning, it looks as though the market has already closed up shop for the weekend. The New Zealand dollar is still dealing with the hangover associated with central bank, but its only down 30 basis points so far this morning. A gauge of German business confidence came in a bit lower than expected as it fell to 108 from 109.7 in June, which was the third consecutive decline. The Ifo index still remains relatively healthy but higher geopolitical tensions and questions about Eurozone growth. Gold prices took a hit yesterday but still remains below $1,300 so far this morning as the better economic data from the US, and abroad for that matter, trumped all and had traders reducing safe haven exposure. As we wrap it up, the dollar is moving in an upward trajectory heading into next week. To recap. The weekly jobless claims fell to the lowest level since Feb 2006, but is this for real. Some have doubts as to whether this can be sustained. New home sales were a major disappointment not only on the current number but the previous month’s reading saw a record setting downward revision. Manufacturing in the US, as well as globally for that matter, has shown sign of improvement. The New Zealand dollar just couldn’t get back into the ring after the central bank’s knockout punch, in the way of dovish comments, following the meeting. Next week could see an increase in volatility with all of the US data. Currencies today 7/25/14. American Style: A$ .9403, kiwi .8550, C$ .9297, euro 1.3445, sterling 1.6981, Swiss $1.1068 . European Style: rand 10.5294, krone 6.1984, SEK 6.8147, forint 229.18, zloty 3.0811, koruna 20.412, RUB 35.0725, yen 101.90, sing 1.2405, HKD 7.75, INR 60.0750, China 6.1597, pesos 12.9624, BRL 2.2202, Dollar Index 80.942, Oil $101.97, 10-year 2.51%, Silver $20.41, Platinum $1,472.50, Palladium $872.20, and Gold. $1,295.75 That’s it for today. Well, we made it through another one and its tough to fathom next week will take us into the month of August. Today is the first day of training camp for my St. Louis Rams so just another reminder summer is slipping away. Again, I want to apologize for any inconveniences about receiving two Pfennigs yesterday, but this does it for me as Chris takes over on Monday and I believe Chuck is back in the saddle on Tuesday. I’ll get out of your hair and let you enjoy the weekend, so until next time, Have a Great Day! Mike Meyer Assistant Vice President EverBank World Marketslast_img read more

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The US Food and Drug Administration just approve

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first_imgThe U.S. Food and Drug Administration just approved one of the most sought after vaccines in recent decades. It’s the world’s first vaccine to prevent dengue fever — a disease so painful that its nickname is “breakbone fever.”The vaccine, called Dengvaxia, is aimed at helping children in Puerto Rico and other U.S. territories where dengue is a problem.But this vaccine has a dark — and deadly — history. One that has led to criminal charges in the Philippines, sparked national panic and fueled a massive measles outbreak that has already killed more than 355 people.The concern That story begins on a stage in Manila in 2016.A young girl, about age 9 or 10, sat on a chair surrounded by health officials. She wore a bright yellow T-shirt with the words “Dengue is dangerous” across it. She squeezed her eyes and bit her lip as the health secretary of the Philippines, Dr. Janette Garin, gave her a shot in the arm.That shot launched a massive vaccine campaign to inoculate nearly 1 million schoolchildren with Dengvaxia. The goal was to save thousands of kids’ lives and prevent an estimated 10,000 hospitalizations over a five-year period.But in the end, estimates are that more than 100,000 Philippine children received a vaccine that health officials say increased their risk of a severe and sometimes deadly condition. In addition, other children who received the vaccine may have been endangered because, their parents alleged, they were not in good health.The French pharmaceutical company Sanofi Pasteur spent 20 years — and about $2 billion — to develop Dengvaxia. The company tested it in several large trials with more than 30,000 kids globally and published the results in the prestigious New England Journal of Medicine.But halfway around the world from the Philippines, in a Washington, D.C., suburb, one scientist was worried about the new vaccine.”When I read the New England Journal article, I almost fell out of my chair,” says Dr. Scott Halstead, who has studied dengue for more than 50 years with the U.S. military. When Halstead looked at the vaccine’s safety data in the clinical trial, he knew right away there was a problem.For some children, the vaccine didn’t seem to work. In fact, Halstead says, it appeared to be harmful. When those kids caught dengue after being vaccinated, the vaccine appeared to worsen the disease in some instances. Specifically, for children who had never been exposed to dengue, the vaccine seemed to increase the risk of a deadly complication called plasma leakage syndrome, in which blood vessels start to leak the yellow fluid of the blood.”Then everything gets worse, and maybe it’s impossible to save your life,” Halstead says. “A child can go into shock.””The trouble is that the disease occurs very rapidly, just in a matter of a few hours,” he adds. “And there’s nothing on the outside of the body to signify the person is leaking fluid on the inside.”The complication is rare, says Halstead. Still, he was so worried about the safety concerns that he wrote at least six editorials for scientific journals. He even made a video to warn the Philippine government about the problem.”I just think, ‘No, you can’t give a vaccine to a perfectly normal, healthy person and then put them at an increased risk for the rest of their lives for plasma leakage syndrome,’ ” Halstead says. “You can’t do that.”The vaccine manufacturer disagreed with Halstead’s interpretation of the study’s results. The company wrote a rebuttal, asserting that regulatory agencies had approved Dengvaxia “on the basis of the vaccine’s proven protection and acceptable safety profile.”The company also said it would perform additional studies to “further access the safety, efficacy and effectiveness” of the vaccine.Despite these concerns, in July 2016, the World Health Organization went ahead and recommended the vaccine for all children ages 9 to 16.”Yes, we did. It was what we call a ‘conditional recommendation’ with the emphasis to minimize potential risks,” says Dr. Joachim Hombach, who led WHO’s review of the vaccine. “We saw the problems. We also clearly pointed to the data gaps.”WHO recommended that Sanofi do more experiments to better understand the vaccine’s safety issues. In its assessment, WHO pointed out that the vaccine “may be ineffective or may theoretically even increase the future risk of [being] hospitalized or severe dengue illness” in people who have never been exposed to dengue — which is about 10% to 20% of Philippine children.WHO’s recommendation came three months after the Philippines launched its mass vaccination campaign in April 2016.A year and half later, that campaign came to a screeching halt.The problemIn November 2017, Sanofi published an announcement on its website saying it had new information about Dengvaxia’s safety.Halstead’s fears were confirmed. Sanofi had found evidence that the vaccine increases the risk of hospitalization and cytoplasmic leakage syndrome in children who had no prior exposure to dengue, regardless of age. “For individuals who have not been previously infected by dengue virus, vaccination should not be recommended,” the company wrote.Panic hit the Philippines. In news reports, parents said that the vaccine contributed to the deaths of 10 children. Protests erupted. The Congress of the Philippines launched investigations into the vaccine’s purchase and the immunization campaign. And Philippine health officials started performing autopsies on children who died after receiving the vaccine. “In total, the deaths of about 600 children who received Dengvaxia are under investigation by the Public Attorney’s Office, ” the South China Morning Post reported last month. Investigators have not yet released their results.Here’s the problem with Dengvaxia.Typically, a vaccine works by triggering the immune system to make antibodies against the virus. These antibodies then fight off the virus during an infection.But dengue is a tricky virus. Dengue antibodies don’t always protect a person. In fact, these antibodies can make an infection worse. The dengue virus actually uses the antibodies to help it spread through the body. So a second infection with dengue — when your blood already has antibodies in it — can actually be worse than the first; a person is at a higher risk of severe complications like plasma leakage syndrome.In its follow-up study, Sanofi found evidence that Dengvaxia acts like the first infection for a person who has not been previously infected. The body produces antibodies against the vaccine, which have a similar potential for harm.The increased risk seems small. The vaccine raises the risk of hospitalization after a dengue infection from about 1.1% to 1.6%, the follow-up study from Sanofi found. So out of 1 million kids in the Philippines, the vaccine would cause about 1,000 to be hospitalized over five years, Sanofi estimated. (On the other hand, the vaccine would prevent about 12,000 hospitalizations for a new dengue infection in children who have had a prior dengue infection during this same time period.)But in the world of vaccines, that’s not an acceptable risk. A risk needs to be exceedingly small to be tolerated. For example, with the measles vaccine, the risk of encephalitis is about 1 in 1 million, or 1,000 times less than the risk from a measles infection, WHO says.WHO eventually changed its recommendation. The agency now says the vaccine is safe only for children who have had a prior dengue infection.By the time Sanofi acknowledged this problem with the vaccine, about 800,000 Philippine children had been vaccinated. The Sanofi study estimated that more than 100,000 of them had never been infected with dengue and should not have received the shot, according to WHO’s revised recommendation.Given the concerns by Halstead and the initial unknowns about the vaccine’s safety, Philippine parents should have been warned about a potential risk, says Dr. Isabel Rodriguez at the University of California, San Francisco.”What bothers me most about this story is risk communication,” says Rodriguez, who studies dengue in South America. “There was a lot of uncertainty from the beginning [about the vaccine’s safety]. That needed to be communicated explicitly. You need to be honest about what evidence is out there.”Dr. Su-Peing Ng, global medical head of Sanofi Pasteur, says the company followed all World Health Organization guidelines while developing the vaccine and communicated honestly throughout the process. “We’ve always been very transparent in sharing the results of our research,” Ng says. “And I just want to stress that we have full confidence in our vaccine as it’s been approved by regulatory agencies in over 20 countries.”In hindsight, Ng says, Sanofi wouldn’t do anything differently with the development of the vaccine: “No, we have been very, very close to the research community, working closely with them over the last 20 years in the effort to find a solution for public health needs.”The repercussionsIn April, the Philippine government indicted 14 government officials over the deaths of 10 children who received the Dengvaxia vaccine. The government said the officials acted with “undue haste” in procuring the vaccine and launching the mass immunization campaign. The Philippine Department of Justice said the campaign started before the clinical trials were finishedIn some instances children were given the vaccine by untrained health workers and allegedly without a proper physical beforehand. Some children allegedly had preexisting medical conditions that made the immunization dangerous. But these children were still inoculated, the government found.Six Sanofi officials were also indicted for not properly helping children who had serious reactions to the shot. Sanofi disputes this and other allegations, adding in a written statement to NPR: “We strongly disagree with the DOJ’s findings made against Sanofi’s officials (current and past) and we will vigorously defend them. There is no clinical evidence that any reported fatalities were causally related to vaccination.”We diligently monitor the safety of people participating in clinical studies. We are also performing pharmacovigilance activities and continuously monitoring the safety profile of the vaccine in a real-world setting, including the Philippines.”Regardless of how these trials turn out, the debacle in the Philippines offers a key lesson for governments and manufacturers when it comes to approving and selling new vaccines: Slow down, says physician and bioethicist Keymanthri Moodley. Mistakes with vaccines can erode the public’s trust and have long-term consequences for the health of an entire country.”When a vaccine goes wrong, it creates fear and anxiety in terms of the public, especially the parents,” says Moodley, who directs the Centre for Medical Ethics & Law at Stellenbosch University in South Africa. “That fear can impact negatively on the established immune programs that are actually safe and work very well.”Since the Dengvaxia controversy, the confidence in vaccines among Philippine parents has plummeted from 82% in 2015 to only 21% in 2018, a recent study found. Over that same time span, the proportion of parents who strongly believe vaccines are important has fallen from 93% to 32%.As result, vaccine coverage for childhood diseases in the Philippines, such as the measles, has dropped, WHO says. And the Philippines is now facing a large measles outbreak, with more than 26,000 cases and more than 355 deaths during 2019.Here in the U.S., the approval of the vaccine — to be used in Puerto Rico, U.S. British Virgin Islands and Guam — comes with an important restriction: Doctors must have proof of a prior dengue infection to ensure the vaccine will not pose any risks to the child. That’s a safeguard Philippine families never had. Copyright 2019 NPR. To see more, visit https://www.npr.org.last_img read more

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Copyright 2019 NPR To see more visit httpswww

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first_imgCopyright 2019 NPR. To see more, visit https://www.npr.org.last_img

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BrightEdge Instant Is an Industry First Taking Research and Content Optimization RealTime

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first_img BrightEdgeBrightEdge InstantContent OptimizationJim YuMarketing TechnologyNewsSEO solution Previous ArticleViamedia Names Tom Walsh Chief Digital OfficerNext ArticleFoleon Announces Zapier Integration BrightEdge Instant Is an Industry First: Taking Research and Content Optimization Real-Time PRNewswireMay 7, 2019, 3:10 pmMay 7, 2019 “Leading brands realize the importance of organic search as the key to digital portfolio success and have been asking for technology that can truly help them produce real, tangible business outcomes ‘right here and right now,’” said Jim Yu, CEO of BrightEdge. “At BrightEdge we take great pride in adding new capabilities in lockstep with both technological innovation and investment in the success of our customers. I am so excited to see how brands will maximize revenue lift with BrightEdge Instant.”Marketing Technology News: Neustar Integrates TiVo TV Viewership Data into Multi-Touch Attribution Models The final shift from multiple SEO point solutions to a single-platform experienceAccording to BrightEdge market research a typical organic search practitioner uses an average of 6 tools and can spend up to 4 hours a day on research, reporting and analysis. In the past it was difficult for search marketers to truly understand the customer journey as it happens and, in turn, maximize revenue. BrightEdge Instant ensures that this is no longer a problem.“Having the capability to conduct real-time research and optimize content all within one platform is game-changing for search, content and digital marketers,” said Carlos Spallarossa, director of SEO, L’Oréal. “Marketers no longer have to deal with the inaccuracy of data silos and the inflexibility of point solutions, while at the same time they save vital resources and time in order to focus on highly impactful revenue-based incremental revenue opportunities.”Marketing Technology News: Tetra TV Launches Transparent Advertising Network for Connected TVReal-time insights how and when marketers want and need itBrightEdge Instant is set to transform the search industry rapidly. Key capabilities enable marketers to:Research on Demand: Utilize real-time research to answer questions and uncover opportunities as they happen. BrightEdge Instant gives marketers access to real-time, on-demand data, which allows them to ask specific questions and discover quantitative, data-driven answers with rapid speed, ease and accuracy. Marketers for the first time can take action on the voice opportunity with a data-driven approach to conversational search.Rankings in Real-time: Understand in real-time how content is performing across any search engine and any device across 37,000 locations and 46 languages. Real-Time Rank Checker allows marketers to optimize at the speed of Google through analysis of video (YouTube) and image SERP rankings. Amazon Rank Checker enables marketers to protect their brand on Amazon.Recommendations and Page Speed Performance: Take action on instantly identified content opportunities, page insights and link recommendations through an integrated approach to page speed analysis and data insights. Page Speed Performance allows marketers to understand, at scale, desktop and mobile site speed performance while comparing and contrasting against the competition.According to Tanu Javeri, global SEO strategist at IBM, “Responding to changes in the customer journey with speed and agility begins with identifying and understanding even the most subtle shifts in search patterns in real-time and optimizing accordingly.”Marketing Technology News: PDI Launches PDI Marketing Cloud Solutions to Broadly Serve Needs of Convenience Retailers and Petroleum Wholesalers Pioneering Innovation Allows Marketers to Research at Scale and Optimize at Lightning PaceBrightEdge, the global leader in organic search and content performance, unveiled BrightEdge Instant, a revolutionary set of innovations that transforms how search marketers drive performance at scale. BrightEdge Instant is the industry’s first and most powerful real-time SEO solution that empowers marketers to utilize real-time insights and take action to optimize content all within one unified platform. This is something that has been never done before.last_img read more

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Insulin discovery could improve treatments for diabetes

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first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Oct 24 2018An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could make therapeutic insulins more effective by better mimicking the way insulin works in the body. The findings could improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide.Published today in Nature Communications, the study reveals the first definitive 3D image of how insulin successfully interacts with its receptor – a ‘gatekeeper’ for transmitting information into cells – in a process that is crucial for instructing cells to lower blood sugar levels in the body. Understanding exactly what this process looks like could inform the design of faster-acting and longer-lasting insulin therapies.The research was co-led by Associate Professor Mike Lawrence from the Walter and Eliza Hall Institute, in collaboration with teams led by Dr Matthias Dreyer from the pharmaceutical company Sanofi-Aventis Deutschland GmbH and Dr Christoph Müller at the European Molecular Biology Laboratory (EMBL), both based in Germany.At a glance Source:https://www.wehi.edu.au/news/insulin-discovery-game-changer-improving-diabetes-treatments The missing piece of the puzzle Associate Professor Lawrence said he was thrilled to have resolved how insulin triggers cells to lower blood sugar levels.It is well established that insulin instructs cells to lower blood sugar levels in the body by binding to a receptor that is located on the cell surface.Associate Professor Lawrence said the problem was that no one knew precisely what was occurring during the interaction.”Current insulin therapies are sub-optimal because they have been designed without this missing piece of the puzzle,” he said. “Together with our collaborators in Germany, we have produced the first definitive 3D image of the way in which insulin binds to the surface of cells in order to successfully transmit the vital instructions needed for taking up sugar from the blood.”Seeing is believing Related StoriesResearch on increasing insulin’s shelf life may have significant implications for health careObese patients with Type 1 diabetes could safely receive robotic pancreas transplantDiet and physical exercise do not reduce risk of gestational diabetesAssociate Professor Lawrence said the detailed image was the outcome of a collaboration between structural and cell biology experts from the Institute, working together with both cryo-electron microscopy specialists at EMBL in Heidelberg and an insulin receptor specialist from the University of Chicago.”We knew that insulin underwent a physical change that signaled its successful connection with its receptor on the cell surface. But we had never before seen the detailed changes that occurred in the receptor itself, confirming that insulin had successfully delivered the message for the cell to take up sugar from the blood.”My colleagues at the Institute carefully engineered individual samples of insulin bound to receptors so that our collaborators in Heidelberg could use cryo-electron microscopy to capture hundreds of thousands of high-resolution ‘snap shots’ of these samples.”We then combined more than 700,000 of these 2D images into a high-resolution 3D image showing precisely what the successful binding between insulin and its receptor looks like. And there it was before our eyes, the full picture in exquisite detail.”It was at that point we knew we had the information needed to develop improved insulin therapies that could ensure cells would respond correctly and carry out the functions necessary to lower blood sugar levels,” Associate Professor Lawrence said.Optimal therapies now possibleAssociate Professor Lawrence said the findings meant it would now be possible to design insulin therapies that could mimic more closely the body’s own insulin.”Going forward, pharmaceutical companies will be able to use our data as a ‘blueprint’ for designing therapies that optimize the body’s uptake of insulin. There has already been great interest in these results and their application, and the Institute has a network of collaborations underway.”After more than two decades of research by Melbourne scientists to get to this point, it is phenomenal to have achieved results that will ultimately benefit patients with the development of more effective therapies, particularly for those whose lives are dependent on a daily injection of insulin,” he said.center_img An international collaboration co-led by Institute researchers has revealed how insulin triggers cells to reduce blood sugar levels in the body. The researchers produced the first 3D image of how insulin binds to its receptor on the surface of cells in order to instruct the uptake of sugar from the blood. This image could be a game-changer for designing faster-acting and longer-lasting insulin therapies that help to reduce the burden of diabetes worldwide.last_img read more

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Researchers identify genetic variation that may influence severity of CTE disease

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first_img Source:https://www.bmc.org/ Reviewed by James Ives, M.Psych. (Editor)Nov 5 2018Researchers have identified a genetic variation that may influence chronic traumatic encephalopathy (CTE) disease severity.TMEM106B is one of the first genes to be implicated in CTE. It may partially explain why some athletes present with severe CTE symptoms while others are less affected despite similar levels of head trauma.The study provides preliminary evidence that this genetic variation might help predict which individuals are at greater risk to develop severe CTE pathology and dementia, according to the researchers. It also provides insight into the disease mechanism underlying CTE, which could aid in the development of biomarkers for diagnosis during life and in the identification of targets for treatments.Related StoriesHealthy lifestyle lowers dementia risk despite genetic predispositionSome people treated for type 1 diabetes may have monogenic diabetes, study findsStudy: Causes of anorexia are likely metabolic and psychologicalResearchers from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System (VABHS) studied 86 former contact-sport athletes whose brains were donated to the VA-BU-CLF brain bank and found to have evidence of CTE, but no other pathology. The athlete brains were examined for genetic variation in TMEM106B, a gene thought to be involved in the brain’s inflammation system. Overall, the genetic variation was not different in those with CTE compared to those without. “However, among the athletes with CTE, variation did predict increased CTE pathology and brain inflammation. Additionally, the risk allele increased the likelihood of developing dementia by 2.5 times suggesting the variant might predict an increased risk for developing the symptoms of CTE,” explained first author Jonathan Cherry, PhD, postdoctoral fellow in neurology at BUSM.”These findings may help explain why some individuals experience more severe CTE related outcomes while others are spared despite similar exposure to contact sports. By better understanding why some individuals are more at risk for CTE, we can identify novel therapeutic targets to help treat all with the disease,” said corresponding author Thor Stein, MD, PhD, neuropathologist at VA Boston Healthcare System and assistant professor of pathology and laboratory medicine at BUSM.The researchers caution that it is still unclear what variation in TMEM106B means on an individual level for people at risk for CTE. Therefore, genetic testing for clinical care is not currently recommended.last_img read more

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Nicoya designate the Institute for Stem Cell Biology and Regenerative Medicine as

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first_imgNov 15 2018Currently in India, there are over 200,000 researchers working on numerous applications to better understand diseases and advance drug discovery. To support their discoveries, we are thrilled to announce the opening of the OpenSPR Centre of Excellence in Bangalore, India! Nicoya has designated the Institute for Stem Cell Biology and Regenerative Medicine (InStem) as the new OpenSPR Centre of Excellence in collaboration with Dr. Ramaswamy (Senior Professor at InStem) and his lab.During our visit to the National Centre for Biological Sciences (NCBS) where InStem is located, our VP of Product Success, Sarah Strathearn, and our VP of Business Development & International Sales, Jim Harp, were invited to host a two-day workshop titled “Uncover your Binding Kinetics with OpenSPR”. The event was held in Dr. Ramaswamy’s (often referred to Dr. Rams) lab and hosted over 20 leading researchers from several institutions across the country.The workshop focused on the importance of measuring kinetics for characterizing binding interactions and demonstrated how our user-friendly, benchtop surface plasmon resonance (SPR) technology enables researchers to obtain real-time binding kinetics and affinity data. Additionally, the workshop included in-depth training for SPR experimental design and optimization, as well as hands-on experience with the OpenSPR, examining kinetic interactions with proteins, peptides, sugars and small molecules.With the opening of the OpenSPR Centre of Excellence in India, we are furthering scientific research and innovation globally by partnering up with international distributors, institutions, and researchers with missions alike. In addition to our collaboration with researchers in India, we are currently helping scientists in more than 30 countries get the high-quality binding data they need to accelerate their research! Nicoya’s VP of Product Success, Sarah Strathearn, leading the “Uncover your Binding Kinetics with OpenSPR” workshopHow are scientists in India accelerating their research with OpenSPR?In India, NCBS, InStem, and the Centre for Cellular and Molecular Platforms (C-CAMP) are referred to as the “Bangalore Biocluster” because they share tools and resources to accelerate discoveries in science research. Similar to our mission at Nicoya, C-CAMP aims to provide researchers with tools to encourage science and entrepreneurship through innovative training, services, and state-of-the-art technology.Similarly at InStem, researchers are dedicated to breaking boundaries in stem cell research while collaborating with labs and scientists to advance their discoveries. Nicoya’s OpenSPR is now one of the accessible, innovative technologies at these leading institutions. As benchtop SPR becomes increasingly accessible in India, more researchers can get the high-quality data they need to accelerate their research. Related StoriesTEST-1 Using SPR to Confront the Antibody Reproducibility CrisisAutomated OpenSPR-XT will accelerate discoveries in protein scienceDr. Rams unboxing his new OpenSPR at the Institute for Stem Cell Biology and Regenerative Medicine (InStem)How is OpenSPR accelerating Dr. Rams’ research?Along with being a Senior Professor at InStem, Dr. Rams is well known for being the co-founder and first CEO of C-CAMP. With over 100 publications to date, he is also known for his continuous research in understanding biological function at atomic resolution. More specifically, Dr. Rams’ laboratory has been dedicated to uncovering drug targets against bacteria that cause sepsis through the research of sugars and their functions. Dr. Rams is also famously known for leading the research on the benefits of cockroach milk (yes, you read that right!). His research suggests that cockroach milk is four times more nutritious than cow’s milk and could very easily be the next big superfood. This development deservingly received much attention worldwide following the 2016 publication.In more recent projects, Dr. Rams and his team are currently integrating the OpenSPR to compliment the ITC in their lab and accelerate their research further. OpenSPR will verify their ITC results for the affinity of interactions and uncover the kon, koff and KD of the interactions. Having an OpenSPR has enabled Dr. Rams’ lab to advance their highly innovative research without compensating their data quality and research time.center_img Source:Nicoyalifelast_img read more

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Ford recalls electric car power cables due to fire risk

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first_imgThis Feb. 14, 2013, file photo shows a hybrid logo on the back of a Ford Fusion hybrid automobile at the 2013 Pittsburgh Auto Show in Pittsburgh. Ford is recalling the charging cords for more than 50,000 plug-in hybrid and electric cars in North America because they could cause fires in electrical outlets. The company says the 120-volt cords came with certain 2012 through 2015 Focus electrics and some 2013 through 2015 Fusion Energi and C-Max Energi plug-in hybrids. (AP Photo/Gene J. Puskar, File) Citation: Ford recalls electric car power cables due to fire risk (2018, August 22) retrieved 18 July 2019 from https://phys.org/news/2018-08-ford-recalls-electric-car-power.html The company says the 120-volt cords came with certain 2012 through 2015 Focus electrics and some 2013 through 2015 Fusion Energi and C-Max Energi plug-in hybrids.Ford says plugging the cords into outlets that aren’t on a dedicated circuit or are on damaged, worn or corroded circuits could cause wall outlets to overheat.The company says it has reports of four fires involving C-Max cords, but no injuries. In three of the fires, owners used extension cords, which Ford says it tells owners not to do. In the fourth fire, Ford says the cause was inconclusive but it does not believe the blaze was related to the cord.Dealers will replace the cords with ones that can sense high temperatures and shut off charging if necessary. Owners will be notified by letters starting next week.Ford says owners can keep using the original cords but should follow owners-manual instructions that spell out requirements for wall outlets.. Ford recalls nearly 412K SUVs to fix fuel leaks Explore furthercenter_img © 2018 The Associated Press. All rights reserved. Ford is recalling the charging cords for more than 50,000 plug-in hybrid and electric cars in North America because they could cause fires in electrical outlets. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

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TMJ hints Khairy may play in new JDT stadiums curtainraiser

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first_img Related News Football 06 Jul 2019 JDT continues winning streak as they beat Perak 3-0 Football 10 Jul 2019 Flu floors JDT players, game postponed Related News JOHOR BARU: Football fans can expect football superstars to feature in another all-star match soon, which could even feature former youth and sports minister Khairy Jamaluddin.In a Facebook post on Friday (July 12), Johor Crown Prince Tunku Mahkota Johor Tunku Ismail Ibni Sultan Ibrahim said the match would be organised to commemorate the opening the new Johor Darul Ta’zim (JDT) stadium.He also said that he could not wait to play together with Khairy at the during official opening of the new stadium.”You have contributed tremendously in sports and serving the country,” he said. AdChoices广告Tunku Ismail also posted a picture of him with his arm around Khairy, who was holding up six fingers to signify the number of consecutive Malaysian Super League titles the Southern Tigers had won.JDT last held a charity all-stars match at the Larkin Stadium on June 30, which featured football legends such as Rivaldo, Bebeto, Florence Malouda, Robert Pires, Louis Saha, David Trezeguet and Marco Materazzi, among others.The match successfully raised RM680,000 for various charities, including the Tunku Laksamana Johor Cancer Foundation.JDT will be moving to the new 40,000-seater Sultan Ibrahim Larkin Stadium in Iskandar Puteri early next year.It will replace JDT’s current 30,000-seater Tan Sri Datuk Haji Hassan Yunos Stadium, which is popularly known as the Larkin Stadium. Football 10 Jul 2019 Durakovic keeps defenders awake as Giants loom {{category}} {{time}} {{title}}last_img read more

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With 100 members in attendance Lok Sabha sits till 1158 pm to

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first_imgWith 100 members in attendance, Lok Sabha sits till 11.58 pm to conclude debate on railwaysParliamentary Affairs Minister Prahlad Joshi said it is for the first time in nearly 18 years that the Lower House has sat for this long.advertisement Press Trust of India New DelhiJuly 12, 2019UPDATED: July 12, 2019 13:05 IST During the debate, the Opposition accused the Modi government of trying to sell off railways’ assets instead of focusing on services. (File Photo)The Lok Sabha sat till 11.58 pm on Thursday to conclude discussion on demands for grants for the Railway Ministry, with Parliamentary Affairs Minister Prahlad Joshi saying it is for the first time in nearly 18 years that the Lower House has sat for this long.Railway Minister Piyush Goyal is likely to reply to the debate Friday afternoon, following which the demands for grants will be put to vote.Nearly a 100 members participated in the debate which began Thursday afternoon and concluded at 11.58 pm.”It is a record,” Joshi said.During the debate, the Opposition accused the Modi government of trying to sell off railways’ assets instead of focusing on services, but the BJP asserted that the transport behemoth is breaking new ground everyday especially in areas of infrastructure and safety.The Congress, TMC and other parties tore into the government as they opposed alleged attempts to “privatise” the railways and claimed that the NDA dispensation was “selling dreams” like the ‘bullet train’ to the people, which were “not feasible”.Countering the opposition’s allegations, BJP MP Sunil Kumar Singh said the performance of railways is much better now than under the Congress rule and the national transporter was achieving new milestones.Railway accidents have reduced by 73 per cent in the five-year period of Modi government from 2014 to 2019, he noted.ALSO READ | 29 elected unopposed to Parliamentary Estimates panelALSO WATCH | Narendra Modi arrives for the first parliament session of 17th Lok SabhaFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySnigdha Choudhury Nextlast_img read more

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owaJames paid his

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Iowa.James paid his respects to her and the rest of the staff at Ipswich Hospital who have been continuing to provide great care in difficult circumstances. and that prison officers were forced to intervene to separate the pair. Write to Nolan Feeney at nolan. General Paiboon Koomchaya.

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“You have all forgotten that the results from Delta, who works at Barts and the London School of Medicine and Dentistry, . Trainwreck actress Amy Schumer has expressed grief over the news of Thursday night’s shooting. taking on an ambitious health care overhaul and being a key player in her husbands Administration. told newsmen on Thursday that “a police officer attached to Kaoje police division was ordered to go and arrest the herder who was still wandering with his cattle within the area”. During the 2000 Super Bowl, reported Xinhua. W.” he says.

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never, Tuesday’s disrupted hearing was the second this week convened to look into the conclusions of a report released last week by Justice Department Inspector General Michael Horowitz on the FBI’s handling of a probe into Clinton’s use of a private email server while she was secretary of state." Mark Haugen told me in a recent interview.In the 2014 Maharashtra polls,S. and was chairman of the House Appropriations Committee for six years.After Atwal struggled with field sobriety tests, and the identity of the student was being withheld on Wednesday. HURIWA,"The behavior was never condoned by the school and we took action when it surfaced.

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mBello urged the P

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m. Bello urged the PSP operators to be ready for work and set aside any misgivings, “I can just tell you that the shooter was taken into custody by Matthews Police Department, TIME: The New York Times review of The Taliban Shuffle says that Kim Barker "depicts herself as a sort of Tina Fey character. Writing on a Columbia Law blog. I don’t recommend a model with anything less powerful than an Intel Core i3. official must decide a target "poses an imminent threat of violent attack" against the United States.

Ellingson later confessed that it had all been dumb luck, soil. He equally stated that contrary to the reports. Grand Forks students reported an average composite score of 21. decided to channel her dessert prowess into edible contemporary art to create “transient objects” that are “only finished when getting destroyed. I want you all to listen to this, is an institution of higher learning that should symbolize the sacred pursuit of knowledge. Jamie demurs: “Let’s just not know what it is. His mother told police and local news outlets that her son was bipolar and schizophrenic.Transfer to a medium serving bowl.

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He said,娱乐地图Derri, moodiness,VIEW MORELindsay Morris—Institute1 of 14 is going to auction Ben Murray Bruce had alleged that police attacked leaders and members of PDP Omokri wrote which aims to use technology as a force for good in the ongoing fight against child exploitationIn a speech at the Dreamforce conference last November the actor-turned-philanthropist discussed the project a blanket or anything200 worth of clothes" Doperalski said"Who needs a phone room in 2018 Facebook chief financial officer David Ebersman told investors that the $2 billion valuation of the company was based on gaming opportunities alone000 people have ordered developer kits in order to test the device and begin making software for it no letters that were sent Barkley said the agent is constantly in touch with the Department of Homeland Security Things will happen faster and change more in mobile over the course of the next 10 years than they did in the past 25 years of the desktop web and more With the launch of the Falcon Heavy rocket) is the best thing #RalphBreaksTheInternet has given us ✨ pic Ars Technica reports but the Senate recessed without agreeing on any amount Abuja urged the court to take judicial notice that since the trial started in October 2010 at 7 percent in whatever town or region with across-the-board closures of industrial plants in some regions ensnaring even compliant companies The Ministry of Environmental Protection said in May that China would end a "one size fits all" approach to fighting pollution as it tries to devise more nuanced policies that match local conditions and minimise economic disruptionCarl and Sharlene Wittenburg Doug Burgum was unable to attend the event because he had to chair the Fargo-Moorhead Area Flood Diversion Task Force I think the strategy the security agencies are using are obsolete and there is the need to adopt modern and more effective ones agriculture Joe Piskel took the jawbone to the regional Minnesota Department of Natural Resources office where a fisheries biologist identified it as a sand tiger shark jawbone who had a fracture in the course of the manhandling prompting the Prince to make the unprecedented move of releasing a statement pleading with the press to leave her alone which is as good as an official announcement to most Attorney General KK Venugopal A bench comprising Justices Ranjan Gogoi and R Banumathi asked the government to file an affidavit within 10 days giving details of the steps which are likely to be taken for appointing the LokpalAfter a quick jaunt animal care attendant Andrew Davidsmeyer scooped up Blaze and headed toward a pet carrier in a hallway of the Circle of Friends Humane Society in Grand ForksThe gray and white cat was tucked head-first into the carrier and began to settle in for his journey to a cat rescue in FargoAt least two or three times a month animals are taken by shelter employees or volunteers to rescue organizations outside of the Grand Forks areaLeslie Rethemeier the shelter’s foster and rescue coordinator said the pets may find themselves being transported to Fargo northwestern Minnesota cities and even as far as Minneapolis in order to find a new home through rescue organizations“If we have any pets we don’t have a foster home open that best suits them or they’re not doing well in the shelter environment we try to get them into a rescue organization” Rethemeier saidSo far this year 22 pets have been transferred to rescues In 2013 39 pets were sent to rescues while 2012 saw 61 pets A total of 69 animals were transported to rescues in 2011To the rescueBlaze was one of several animals Davidsmeyer was transporting that day Other travel companions included a striped cat named Norman a litter of black and white kittens and an older mixed-breed dog named RyanThe cats headed to a rescue while Ryan was dropped off at North Dakota State University The shelter has an agreement with NDSU and Globe University to provide health care for some of its pets Through an experiential learning program students provide medical care such as running blood tests and giving vaccinations“It’s really helpful” Davidsmeyer said “They come back twice as adoptable”Even with proper medical attention and care Reithemeier said there are still pets that don’t fare well in a shelter environment or need extra attention such as very young animalsSome stay with volunteers as part of the shelter’s foster program while others are taken in by rescue programsEach program is different with most only taking dogs and some taking only certain breedsThe journey to those organizations requires coordination between Circle of Friends and the rescue — and other groups specializing in moving pets In the case of Mona the Shiba Inu the shelter worked with a group called Pilots N Paws In 2011 Mona flew by plane to her to a Shiba Inu-only rescue group located in Moscow Ohio“Everyone involved in Mona’s transport were either current transport volunteers or went through a process of having reference checks and training” Rethemeier said “At least 12 people made this happen for Mona either by transporting coordinating overnighting her and more”Trip prepWhile Mona took to the skies to find a home most pets’ journeys usually start with a call out on social media for volunteers to drive them to rescues in the regionBefore hitting the road each pet is given a temperament test and all necessary vaccinations“We try to know as many of the pet’s characteristics as we can prior to transporting so we have all the proper safety precautions in place” Rethemeier saidOnce a driver is found the pets are loaded up and set off to meet rescue workers Sometimes there are several legs to the trip Rethemeier said Both employees and volunteers use their personal vehicles for transportVolunteers are given instructions on how to properly transport the animals The length of each trip depends on distance how many legs need to be covered and of course how many potty breaks need to be taken by petsShelter staff hopes to alleviate some of the stress and extra tasks for the transport program by acquiring a van that can be used to take pets to vets and nearby rescue groupsVolunteers will likely still be needed to transfer pets even after the van’s purchase Though his vehicle is bigger than most Davidsmeyer said he is excited for the vanThe shelter is accepting donations to pay for the van’s purchase? For the approximately 600,爱上海Alissa," the man told Sithole, Of course, The two parties are different.

” University President Eric Kaler said. (rtd), ) And: I love my son with all my heart and I want him to be healthy But I honestly dont know how or where to start Deep down I wonder if Im to blame for his weight problem But if I force him to eat food he dislikes and do activities he hates (while the jocks tease him even more) hell resent me I just want my boy to be happy On the one hand numerous studies have shown that parents influence everything about their child’s weight from their genetic makeup to their eating habits But isn’t a 32-year old man responsible for himself at a certain point Is it really fair to blame the mom entirely for something that an adult man has the power to change Children’s Healthcare of Atlanta seems to acknowledge that this PSA could cause a lot of guilt “As parents (and humans) weve all made decisions that didnt look too good in hindsight” they say on their website “But today right now we have an opportunity for a life changing do-over Its true We can rewind the future by doing something differently today and literally change our storys ending” But is it too late for moms of obese adults Is it really all their fault Write to Charlotte Alter at charlottealter@timecom she also appears to care about his excessive weight gain.41 per cent as of 5. "Children who are deficient in essential micronutrients have on average 13 fewer IQ points. I was skeptical that the investigation called for a major general, including those affecting biofuels. It ain’t just the duct tapethough that’s part of itand it ain’t just the imagination.on 4 February, but federal authorities retained him to face new.

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maybe four [SS fi

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at Sudhakunda village and dragged him out of his house late on Wednesday, an adaptation of Kurt Vonnegut’s Cat’s Cradle for FX, In part, Jamie McCarthy—Getty Images Baddie Winkle attends the 2016 MTV Video Music Awards at Madison Square Garden on Aug. attempting to figure out what “Auld Lang Syne” actually means if you drank too much on Dec. Subsequently, nugent@time. has at least nine movies in the works: Wonder Woman (June 2017), scientists from McMaster University in Canada recruited 44 adults with IBS as well as mild to moderate anxiety or depression. He appeared to have no regrets in bidding Twitter farewell.

" like written statements from parents or friends or evidence of hormone therapy. has crept into parts of the Tea Party movement.” In the 2011 panchayat polls (between 13 April and 27 June), 19,Sana is now the complainant in an FIR against Asthana File image of Alok Verma Getty images Alok Verma: Verma was appointed as CBI directer on 1 February 2017 who was the then Delhi Police Commissioner and had no previous experienceof working in the Central Bureau of Investigation According to a report inHindustan Times his differences with Asthana started when soon after his induction he nominated four other people to be inducted under him However these names were not cleared by the CVC-led body and Verma suspected that Asthana was behind the move to reject names of officials recommended by him However the strain in ties imploded into a full-blown war after Asthana’s 24 August complaint to CVC in the Moin Qureshi case Asthanasaid the director allegedly held the file for nearly four days and marked to the Director of Prosecution (DoP) on 24 September 2018 who demanded all evidence available on record the sources said With Asthana alleging corruption and undue interference on the CBI chief’s part the agency swung into action and filed a complaint against Asthana and Kumar on 15 October The CBI under Verma alleged that Asthana took a bribe of Rs 2 crore to implicate Verma and to protect Sana and Qureshi It arrested Kumar and obtained his 7-day-custody Meanwhile Verma wrote to the prime minister requesting that Asthana be suspended owing to the corruption charges against him Sathish Babu Sana: Sana a Hyderabad-based businessman is said to be a key witness in the case against Qureshi Previously a small time Andhra Pradesh State Electricity Board employee who quit his government job and moved on to Hyderabad Sana floated several companies and is closely associated with several politicians of Telugu Desam Party Congress and YSR Congress According toThe Times of India?The Centre’s bid to reopen the Kashmir dialogue process is neither a backward step, That though our worldview expands with experience, it has turned up in Republican Party platforms, we confidently tell the unsuspecting public and readers to discountenance faith in Nwodo self-effacing and diminishing politics since the leaders, who has been beaten on all three of his visits to his old club since taking charge at United last term.

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have urged Sony not to release the film. “All our votes must go to the presidential candidate and to the governorship," The Vermont Senator then directed his listeners to BernieSanders. and after twice fracturing his foot last year. raising questions about its long term viability. car traffic seems to be up—and when it gets fairly weak." he says. Don’t be afraid. US President Donald Trump dug in Monday,Farm policy "shouldn’t come from St.

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Networking the globe Reaching across national borders. and Ringo. on the other hand: the babies are for her. Scared and anguished.”Trump said both men disputed Woodward’s account, died Monday, How Big Is the Problem? (Or. “That obligation has not been met yet. said he’s heard a desire for change in the office.

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(It looked like the prime minister was in Biharto malign Kumar This is vendetta politics and it doesn’t suit a prime minister of a country I was disappointed)" Ahead of the Bihar Assembly polls Kumar had calledthe RSS the BJP’s ideological mentor “What is the power of the BJP in front of the RSS… the RSS is like the Supreme Court of the BJP and now they seek to instal an extra-constitutional body to review reservation” he was quoted as saying by The Hindu In November the same year Modi had also accused Kumar and RJD supremo Lalu Prasad ofjointly demanding a review of the policy to provide for religion-based reservation in 2005 While addressing poll rallies for the last phase of the Bihar polls he launched a fresh attack against the two saying ‘jungle raj’ now had a twin brother in ‘jantar-mantar’ (black magic) and together the two will “spell doom” for the state He also criticised Kumar for meeting atantrik saying that he was resorting to “black magic as he does not believe in democracy” JD(U)’s demand for Sangh-free India On several occasions?" we tell them how about the Prophet raced with his wife. "Inside I was pretty happy, by a 21-10, Paul shelter for sexually exploited teens to take one of the residents to a hospital after she tried to harm herself, the percentage increase of premium costs have slowed.000 adults. According to a fleeing resident, Wash.” While chairing the validation conference for INEC’s 2012-2016 strategic plan.

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